New Hormones Can Revolutionize Diabetes Treatment

Diabetes mellitus now affects more people than ever, with nearly one in ten Americans suffering from it, and the number of diabetics in developing countries is growing rapidly. And while treatments are constantly improving as research progresses, the currently available therapeutic options are far from ideal. But a major breakthrough in diabetes research recently reported by a group of scientists in the journal Cell Phone offers a new hope for radically new and improved ways to combat this disease.

The research team at Harvard led by Douglas Melton focused on the pancreatic beta cells that are responsible for the production of insulin. In type I diabetes, these cells are gradually destroyed by the body’s immune system, and in type II diabetes, but at some point begin to fail as the disease progresses, making them a prime target for possible new therapeutic approaches for diabetes. In healthy people, beta cells usually divide at a rather sluggish rate, with the total remaining more or less constant. But it has been known for some time that under certain conditions, such as pregnancy, they can multiply much faster. The aim of the scientists was what exactly triggers this proliferation, and whether this will then be used to increase their numbers for therapeutic purposes.

Working with mice as model animals, she first devised a way to replicate her body’s perception as if insulin lacked what they hoped would replicate the beta cells faster. They did this by using an injection of insulin receptor antagonists, which prevents the insulin binding to its receptors in different tissues, effectively blocking its action. The effect of this blockade turned out exactly as they had hoped: when mice were given the insulin antagonist, their beta cells responded rapidly by dividing faster and more numerous.

New-Hormones-Can-Revolutionize-Diabetes-Treatment

Once the beta cells were awakened in division faster, the scientists were able to investigate what mechanism lay behind this effect. First, they quickly ruled out the possibility that the insulin antagonist acted directly on the beta cells. This could then only mean that another substance released to other tissues and acting on the beta cells in the pancreas – a description incorporating a hormone – had to be responsible. How many hormones are peptides and thus encoded by specific genes, then researchers decided how the administration of insulin antagonists affects gene expression in different tissues. In particular, a gene caught their attention because its expression in liver cells greatly increased in response to insulin receptor blockade. Furthermore, this gene had some properties that it encodes for a peptide secreted from the cells, as suggested for a hormone. They called the gene and its product betatrophin, which comes from the Greek and translates into about ‘beta nutritious.’ Importantly, humans also possess a betatrophin gene and the hormone is also produced in the human liver.

The last step was to show that they really found the right substance. Instead of trying to isolate betatrophin or somehow produce and inject it into the mice, additional copies of the gene are inserted betatrophin them into the liver cells, thereby significantly increasing the production of the hormone. The beta-cell response was fast and vigorous: once betatrophin production started in the liver, its proliferation rate increased by more than 30-fold! As a result, the pancreas of the mice was elevated in betatrophin able to produce larger amounts of insulin, to the point that glucose tolerance was even better than that of healthy mice.

Extrapolating these results to humans, it is not difficult to imagine what this means for diabetics. Injecting betatrophin once a week, for example, would increase the proliferation of their ailing beta cells, increasing insulin production and ensuring natural glycemic control – which is far better than having to rely on insulin injections.

Of course, it is far too early to celebrate a new revolution in diabetes therapy. It remains to be seen if the results in mice are also reproduced in humans; It has happened before that results that very promising mice could be replicated in human clinical trials are being sought. We thus have to wait for further studies, and until scientists are able to produce enough to try it in betatrophin humans, we can not be sure what to really expect.

But the discovery of a new hormone that can increase the proliferation of insulin-producing cells is still exciting news. Because even if the further research ultimately proves disappointing, or shows that the real story behind betatrophin is more complicated than it looks now, there will still be radically new leadership in the search for better treatments for diabetes – and with it the hope for a healthier and longer life for the billions of diabetics worldwide.

Tips How to Raise HDL and Lower LDL

How to raise HDL and lower LDL tips need to be followed so that you are able to control the level of your cholesterol. There are 3 types of cholesterol, the first is HDL (High Density Lipoprotein) which is the good kind of cholesterol. The second is LDL (Low Density Lipoprotein) which is the bad kind of cholesterol and the last is Triglycerides. Those 3 types of cholesterol needs to be balanced in your blood. Here are some tips how to raise HDL and lower LDL cholesterol.

How to Reduce LDL Level
    1. Exercise routinely

Exercise such as Yoga, Aerobic, Taichi, cycling, swimming, and jogging can be done. But the important thing is the exercise should be suitable with the age and ability of the person who has high level of cholesterol. Work out for 3 minutes 5 times in a week is able to increase the level of HDL and reduce the level of LDL effectively. There are a lot of benefits of working out for your health such as getting the toxic out of your body through sweat, keeping your heart healthy, and keeping your body weight in ideal number.

    1. Consume More Fruits and Vegetables

Fruits such as pomegranate, orange, grapes, and olive is good at reducing the level of LDL cholesterol. Consuming fruits and vegetables is able to reduce the risk of getting high level of cholesterol because those fruits and vegetables contain a lot of fibers and antioxidant which are really good at dissolving fats and getting it out of your body. Change your snacks with fresh fruit or vegetables salad.

    1. Stop Consuming Alcohol

Quit consuming alcohol is the next tip how to increase HDL and lower LDL. Consuming alcohol is not only able to damage your liver but also increase the level of the bad kind of cholesterol. Consuming alcohol has the effect of increasing blood pressure, body weight, and also cholesterol. Moreover, consuming alcohol has the negative effects directly for your heart, such as irregular heart beat and the failure of heart pump.

how-to-raise-hdl-and-lower-ldl

How to Raise HDL Level
    1. Quit Smoking

The first tip of how to improve HDL and reduce LDL is by stop smoking. There is chemical content in a cigarette which is called Acrolein. This content is able to stop the activity of the good kind of cholesterol or HDL bringing fats to your liver so that it causes artery narrowing or Atherosclerosis. It can be concluded that smoking is the main factor for a person to get heart attack disease or stroke.

    1. Consume Foods that Contain Omega 3 Fatty Acids

Omega 3 fatty acids will not affect the level of LDL, but it is able to increase the level of HDL and reduce the blood pressure. Some kinds of fish such as herring, salmon, and mackerel contain this omega 3 fatty acids. Or you are able to consume almond or walnut to get omega 3 fatty acids. This is also a tip how to raise HDL and lower LDL.

Facts About Vanilla Ice Cream

Is vanilla ice cream gluten free question is the most asked question by those who love ice cream, but need to limit the consumption of sugar. The sweetness and coldness of an ice cream will help you to be more relaxed and free from the stress. But, what about those who got diabetes? Is it true that diabetics need to avoid consuming ice cream at all?

How to Consume Vanilla Ice Cream for Diabetics

Food for diabetics mostly contains less sugar and fat, it is because diabetics need to control their blood sugar levels by limiting the consumption of sugar. This makes all kind and all flavor of ice cream which contains high level of sugar becomes the biggest enemy for diabetics. Maybe some diabetics make some excuses like, is vanilla ice cream gluten free? Or is all vanilla ice cream gluten free?

Actually, diabetics still can consume ice cream. People with diabetes can consume ice cream with low sugar, low calories and low fat. There are some ice cream brand that produce gluten free vanilla ice cream. For example, Breyers. Breyers produce healthier vanilla ice cream which is without extra sugar, lactose free, fat free, and low carbohydrate. This may answer your question about is Breyers vanilla ice cream gluten free.

is-vanilla-ice-cream-gluten-free

If it is hard for you to find gluten free ice cream in your town, especially gluten free vanilla ice cream, you can make it yourself. Use sugar with low calories and low fat milk. You can also add some fresh fruit to make it healthier and safer for your blood sugar. By making your own vanilla ice cream, you can also control the sugar level. 

Benefits of Consuming Ice Cream

You should not only ask is vanilla ice cream gluten free, you should also ask the benefits of consuming ice cream. Not only relieving stress and calming, there are also other benefits you can get and here they are.

    1. Consuming ice cream can strengthen your bones. It is because ice cream is mostly made from milk which is the good source of calcium. This can be a replacement if you cannot drink milk.
    2. Ice cream is your source of energy. Ice cream contains high level of nutritional value such as carbohydrate, fats, and protein. All of them are important as your source of energy to help you doing your daily activities.
    3. Ice cream is able to increase your immune system. It is because ice cream contains lactoferrin, which is useful to prevent your body from viruses such as influenza and cytomegalovirus.

Consuming ice cream is able to stimulate your brain. It is because ice cream contains thrombonin which is playing a role in decreasing stress. Besides, ice cream is made from milk which contains L-triptophane which is nature sedative to make your nervous system relax. It is even claimed that consuming ice cream is able to avoid you from insomnia. Those are the benefits of consuming ice cream beside the answer of is vanilla ice cream gluten free.

Tips to Have Breakfast Fast Food for Diabetics

Gluten free breakfast fast food is the mostly searched fast food by diabetics who still want to eat fast food. Diabetics are suggested not to eat fast food, even normal people with healthy condition are not suggested to eat fast food too often. Actually, you still can eat fast food although you have diabetes. You just need to pay attention at the limitations when eating it. Here are some tips of ordering breakfast fast food for diabetics.

Things to be concerned in Ordering Breakfast Fast Food
    1. If you want to choose breakfast fast food in combo, ask the waiters to change the French fries with salad or fresh fruits to replace it.
    2. Do not order the jumbo size. Jumbo size or deluxe size means a bigger serve or fast food which also means more calories contained in the food. It also means that it contains more saturated fats, salts, and also cholesterol. It will be better if your order gluten free breakfast sandwich fast food if it is available.
    3. Get used in ordering fast food without topping. If you cannot find gluten free breakfast fast food, choose the common fast food without adding any topping on it. Do not add tomato sauce or mayonnaise. If you order sandwich or burger, order one without cheese and ask the waiters to add some tomatoes and onions.
    4. Choose to eat salad as your side dish. Choose salad instead of garlic bread or mac and cheese as your side dish. Mix bell pepper, broccoli, spinach, garlic with some fruits such as strawberry, melon, watermelon, and etc. As the salad dressing, you can add mustard instead of mayonnaise.
    5. Eat healthy snacks after you eat breakfast fast food. You can eat fresh fruits or plain Greek yogurt as your snacks to replace the unhealthy ones. You can order them in the gluten free fast food breakfast restaurant or you just can bring them from your home.

gluten-free-breakfast-fast-food

DIY Gluten Free Breakfast Fast Food Menu

If it is difficult for you to find gluten free breakfast fast food restaurant in your town, you can make these simple menu for your breakfast fast food.

    1. Scrambled Eggs

Scrambled eggs is the common breakfast menu even in the fast food restaurant. But you cannot control the ingredients they use if you order it that kind of restaurant. So, it will be better if you cook it yourself since it is really simple. Fry the eggs with pure olive oil instead of cooking oil or vegetable oil. Add some vegetables and mashed potatoes or boiled potatoes to make it even healthier.

    1. Sandwich with Wheat Bread

Making sandwich with wheat bread is healthier than using the common bread. Wheat bread is healthier because it contains a lot of vitamin E. You can even choose the healthy filling such as spinach, tomatoes, onions and any other healthy vegetable. Or you can make your own fruit jams as the topping. This simple menu can also be your gluten free breakfast fast food.

Where To Sell Diabetic Test Strips In Albuquerque

Where To Sell Diabetic Test Strips In Albuquerque

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