A vegetable dye appears to have the potential to protect passive smokers from tobacco-related lung cancer, according to a November 2016 study. The substance is found in oranges, red peppers, squash, and many other fruits and vegetables. It’s called beta-cryptoxanthin and it can reduce the number of receptors that nicotine docks to in order to accelerate tumor growth. This tip is particularly valuable for passive smokers because they do not want to – in contrast to smokers – expose this additional cancer risk factor.

The substance in fruits and vegetables protects the lungs from cancer

Nicotine is the addictive substance in tobacco and some e-cigarette liquids. It protects cancer cells, ensuring that they really blossom. To do this, the docks on to their receptors and in this way encourages them to grow more.

Dr. Xiang-Dong Wang is a cancer researcher at Tufts University in Boston. Since 2004 he has been researching carotenoids, the dyes that give color to many yellow and red fruits. Wang tries to find out why these substances can prevent so many chronic diseases. In particular, the carotenoid beta-cryptoxanthin is the focus of his investigations. The substance is in z. In the following foods:

  • oranges
  • tangerines
  • pumpkins
  • Red peppers
  • in many other oranges, yellow and red fruits, and vegetables
  • and also in green leafy vegetables, where the dye is covered by green chlorophyll

The current study by Dr. med. Wang and team were published in the journal Cancer Prevention Research and described how beta-cryptoxanthin (BCX) reduces the number of nicotine receptors, thus reducing the motivating influence of nicotine on lung cancer cells.

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Lung cancer-the most dangerous type of cancer

Dr. Wang says the new research shows how well eating fruits and vegetables can reduce the lung cancer risk of (passive) smokers.

Lung cancer is the type of cancer that causes the highest mortality each year. In Germany, nearly 50,000 people get lung cancer each year. There is over 220,000 new lung cancer diagnosed annually in the US, and over 150,000 people die of it.

Smoking is considered one of the major risk factors for lung cancer. According to the American Lung Association, a man can increase his lung cancer risk 23fold if he smokes. In contrast, a smoker has an “only” 13 times higher lung cancer risk than non-smokers.

However, it is particularly bad that passive smoking alone in the US alone causes over 7,000 deaths each year. Here people have to suffer and die because other people smoke ruthlessly in their presence.

Nicotine accelerates tumor growth

Tobacco smoke contains 7,000 components, many of which are carcinogens that can cause severe damage to the cells of the lungs and bronchial mucosa. So far, nicotine has not been considered a direct cause of lung cancer. However, studies have since shown that the addictive substance can accelerate the growth of lung tumors. Nicotine is therefore even very heavily involved in the development of lung cancer.

For example, in 2013, Warren and Singh wrote in the Journal of Carcinogenesis that it has long been known how badly lung cancer therapies work if the patient continues to smoke. The reason for this is that nicotine and its metabolites accelerate tumor growth in many different ways. For example, angiogenesis is promoted (formation of blood vessels to the tumor, so that it is better supplied with nutrients), the resistance of the tumor to therapies and also directly to the metastasis.

Nicotine causes a strengthening of the cancer

Wang and colleagues have now discovered that nicotine binds to the receptors on the lung surface, leading directly to a signal cascade, which in turn results in rapid cell division of cancer cells and the formation of new blood vessels for tumor delivery (angiogenesis).

Not only that, nicotine can also increase the number of these receptors – and the more nicotine receptors there are, the better the cancerous effect of nicotine. However, as Wang and his team believe, BCX appears to be effective in reducing the number of these receptors, which could now also lead to shrinkage of the tumor.

The more carotenoids (passive) smokers eat, the better they are protected

In earlier studies, Wang’s team had discovered a link between the frequent consumption of BCX-rich foods and a lower lung cancer risk in humans. In animal studies, the suspicion confirmed: who received BCX, experienced shrinkage of his lung tumors by 52 to 63 percent. BCX levels that are similar in humans to one red pepper or two tangerines per day have been effective.

Cell experiments were also performed. It also showed that the cells scatter less frequently in the presence of BCX than without BCX. Who is damned – for whatever reason – to passive smokers, should absolutely eat as healthy as possible, taking care to eat as many carotenoid-rich foods daily as possible.

A vicious circle – the best way to describe the interaction of blood pressure with nicotine. At the end of the cycle, in addition to numerous organ diseases, there is also a heart attack. Although the summary of the problem can be expressed very simply, the actual process is highly complex. In addition, smoking addiction can also act as an enhancer of existing blood pressure problems.

The interaction of the organs

The causes of the rise in blood pressure caused by smoking addiction are three main factors. Specifically, they would be bad enough in and of themselves, but their inevitable interaction within body mechanisms makes them even more of a threat.

Sympathetic activity: The sympathetic nervous system is that part of the autonomic nervous system that controls the regulation of blood pressure as well as metabolic and respiratory functions. Under the influence of nicotine, however, this control mechanism gets out of balance and among other things causes an increase in heart activity and resistance within the blood vessels. The result is cardiac arrhythmia and partial to complete occlusion of the vessels.

Vessel constriction: As a result of the imbalance in the sympathetic or as a direct effect of smoking addiction, the narrowing of the blood vessels forms the core aspect of nicotine-related hypertension. Responsible for the vascular closure is not only the nicotine per se. Also contained in cigarette smoke additives may favor the arterial closure. Furthermore, the circulation and pumping capacity of the heart and blood vessels are severely impaired by the harmful substances, which offers hypertension further bases for manifestation. In this context, the danger of blood thickening caused by the smoke should not be underestimated, which may lead to further blockage of the vessels.

Lack of oxygen: Since the cigarette smoke a large amount of carbon monoxide gets into the blood, with permanent nicotine consumption and the supply of organs, especially the heart, with oxygen at risk. Now O2 is of essential importance for the integrity of the organs and their functionality. A deficiency supply, therefore, brings about serious organ damage. Heart attacks and strokes are thus the worst danger when smoking, while hypertension in this area, merely ‘a precursor to the complete failure of the heart.

Hypertension-and-Smoking-Addiction

The interaction of risk factors

The exact value of systolic blood pressure increase is between 7 mmHg and 10 mmHg when smoking. However, further increases may be added if smoking is associated with one of the following aspects.

  • Smoking due to stress in most cases implies that high blood pressure is already present before consumption. This results from the increased heart activity that results from stressful situations.
  • The same applies to cigarette consumption in combination with obesity. In addition, weight-related arteriosclerosis and vasoconstrictive substances meet and, together, provide even greater resistance within the blood vessels.
  • Smoking addiction in concert with alcohol can not only increase the risk of hypertension but also of cardiac arrhythmia. As nicotine constricts the vessels, alcohol temporarily expands them so that the pumping intervals of the heart become completely out of balance.

Also in connection with lack of exercise or a wrong diet. The risk of high blood pressure by smoking is greater than normal. In addition to the dysfunctional properties of nicotine here are still added to a nutrient deficiency or resilience problems that affect the activity of the heart and organs. Already existing dysfunctions of the organs, such as those caused by unhealthy foods or too little exercise, are further expanded by smoking cigarettes.